Adaptogen Immune

120 Capsules

$46.00 – or subscribe and get 10% off

  • Builds resistance to stress
  • Provides robust support for the immune, nervous, and endocrine system.
  • Protects and supports the adrenal glands

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Description

This is the ultimate adrenal stress adaptation and immune support supplement.

Adaptogens build resistance to stress and bring the body into a balanced state called homeostasis. Adaptogen Immune as a dietary supplement provides robust support for the immune, nervous and the endocrine systems. The goal is greater resilience to stressors on your system, meeting the demands of the environment with ease. 

Adaptogen Immune protects and supports the adrenal glands, strengthens responses of the neuroendocrine system, and encourages the immune system to balance itself. It’s a great product to support blood pressure if yours is too low due to the concentrated licorice. Rhodiola, Ashwaganda, Sutherlandia, Eleutherococcus and Panax ginseng improves recovery from physical fatigue during long-term stress.

Main Actions and Effects:
• Adaptogenic, exerts a normalizing effect during stress
• Strengthens and balances immune system
• Improves physical fatigue from long term stress
• Strengthens the adaptive response in the hypothalamic-pituitary-glandular system
• Promotes healthy cortisol metabolism which improves healthy stress responses
• Blood pressure support in hypotension and POTS
• Hematopoietic
• CNS anti inflammatory and restorative.

Ingredients: Ashwagandha Root (standardized to 4.5% withanolides) 750 mg, Astragalus Root Extract 300 mg, Sutherlandia frutescens 250 mg, Eleutherococcus root Ginseng Extract (standardized to 0.8% eleutheroside) 250 mg, Bromelain 2400 GDU/g 150 mg, Rhodiola rosea (standardized to 1% salidrosides & 3% rosavins) 125 mg, Panax Ginseng (standardized to 80% ginenosides) 100 mg, Licorice Root 20:1 Extract 75 mg.

120 Vegetarian Capsules

Take 3 capsules 1-2 times per day or as directed by your health care practitioner. Can be taken with or without food.

Other Ingredients: Cellulose (from vegetarian capsule).

This product contains no hidden, excipients, binders, fillers, artificial colors, fragrance, wheat, dairy, corn, fish, egg, shellfish, tree nuts or peanuts.

What's Inside

Ashwagandha Root (standardized to 4.5% with anolides)

Withania somnifera [Ashwaganda] is also known as Indian ginseng. It is used in Ayurveda to promote physical and mental health, rejuvenate the body in debilitated conditions and increase longevity. Ashwagandha improves memory and behavior from sleep deprivation. On the cellular level, Ashwagandha improves stress tolerance through improved expression of proteins involved in synaptic plasticity, cell survival and apoptosis in the hippocampus region of brain. The Hippocampus is part of the limbic system which regulates emotions, establishes new memories and forms long term memories. In a sleep deprivation stress study, Ashwagandha demonstrated anxiolytic, anti-inflammatory and anti-apoptotic properties in behavior. Hippocampal inflammatory and apoptotic cytokines IL-6, TNFα, NF-κB, AP-1, Bcl-xL and Cytochrome c were notably decreased as compared to the control group. Ashwagandha suppresses neuroinflammation via attenuating the proliferation of activated microglia, attenuated the TNF-α, IL-1β, IL-6, RNS, and ROS production via down regulating the expression of inflammatory proteins like NFkB and AP1 and also restricted the migration of activated microglia by down regulating metalloproteinase expression. In an oxidative stress rat brain ischemia study, Withania increased glutathione biosynthesis, caused a significant increase in SOD, CAT and GPX activity in neuronal cells and reduced neuro-degeneration in the hippocampus region. Ashwagandha enhanced antioxidant capacity against the adverse effects of free radical production during ischemia and re-perfusion.*

Astragalus Root Extract

Astragalus membranaceus root [milk-vetch] is a tonic herb used for centuries for general weakness, chronic illnesses, and to increase overall vitality. Astragalus increases the number of stem cells in bone marrow and lymph and encourages their development into active immune cells. It also enhances the body’s production of immunoglobulins and stimulates macrophages. Astragalus can help activate T-cells and natural killer (NK) cells. Astragalus has the properties of intensifying phagocytosis of reticuloendothelial systems, stimulating pituitary-adrenal cortical activity, and restoring depleted red blood cell formation in bone marrow. Also, it is famed for its antimicrobial, antiperspirant, anti-inflammatory, diuretic and tonic effects.*

Sutherlandia frutescens leaf

Sutherlandia frutescens [Cancer Bush] is a medicinal plant that has been traditionally used in southern Africa for cancers, infections, inflammatory conditions and oxidative conditions. Sutherlanndia is rich in plant polysaccharides with a pectin-like structure which activate macrophages, increases production of NO, ROS, and inflammatory cytokines/chemokines. Sutherlandia promotes glutathione levels in normal cells, decreases glutathione in cancer cell lines and acts as a ROS scavenger. Sutherlandia demonstrates strong immune system boosting activities. In the CNS immune system, Sutherlandia suppress NMDA- induced reactive oxygen species (ROS) production in neurons, and LPS- and IFNc-induced ROS and nitric oxide (NO) production in microglial cells.*

Eleutherococcus root Siberian Ginseng Extract (standardized to 0.8% eleutheroside)

Siberian ginseng [Eleutherococcus] is the ultimate example of an adaptogen that increases resistance to physical, chemical and various biological stressors. In addition to its anti-fatigue and anti-stress effects, the plant also exhibits immuno-modulatory effects - specifically anti allergic effects with less histamine release by mast cells activated by allergens. In the hypothalamic-pituitary-adrenal system, eleutherococcus modulates the functioning of the system depending on external factors and stressors. Eleutheroccus is an adrenal tonic, useful for both overworked and damaged adrenals. Eleutherococcus helps the body adapt to a varied platter of stressors. Better stress adaptation allows for more energy, greater endurance, and improved responses capacity to stressors in one's life.

Panax Ginseng (standardized to 80% ginenosides)

Panax ginseng, [Red Korean ginseng] root is a foundational immuno-modulator and adaptogen. In a 2014 study Korean Panax ginseng extract significantly enhanced NK cell cytotoxic activity by 35.2% and 40.2% from baseline after administration for 8 and 14 weeks, respectively. The phagocytic activity of peripheral blood cells was also significantly increased by 25.2% and 39.4% and serum level of TNF-α by 38.2% and 44.5% after treatment for 8 and 14 weeks, respectively.13 Ginsenosides from ginseng protect human endothelial cells against influenza H9N2-induced inflammation and apoptosis. In an in vivo human study, ginseng extract improved the survival of human lung epithelial cells against RSV infection and inhibited RSV replication. Ginseng extract also significantly reduced RSV-induced inflammatory cytokine genes (IL-6 and IL-8) and the formation of reactive oxygen species in epithelial cell cultures. Other in vivo effects includes enhanced level of interferon-γ (IFN-γ) by dendritic cells subsequent to RSV infection. Ginseng protects animal models from developing chronic lung infection by P. aeruginosa. Ginseng aqueous extract significantly prevented P. aeruginosa from forming biofilm and destroyed most 7- day-old mature biofilms after a 24hr in vitro exposure. In several in vivo animal studies, Ginseng treatment significantly enhanced bacterial clearance from the lungs and reduced the severity of lung pathology in animals with artificial P. aeruginosa biofilm pneumonia, compared with the control groups. Ginseng root up-regulated the Th1 immune response and down-regulated the Th2 response in chronic P. aeruginosa infected animals, which favored the host to clear the bacterial infections and reduced inflammation. In an in vivo rat malaria model, Ginseng polysaccharides resulted in significantly stronger phagocytosis by peritoneal macrophages and it showed a synergistic anti-malaria effect with artesunate, likely from activation of immune responses. Panax ginseng extract's effect on the immune response to vaccination was studied. NK-cell activity for the ginseng group was double that of the placebo group (p<0.0001) at weeks eight and 12. Serum antibody titers were 272 units in the ginseng group compared to 171 units in the placebo group. A significant decrease in the frequency of upper respiratory infections during weeks 4-12 was noted in the treatment group compared to placebo; 15 cases versus 42 cases, respectively. Ginseng has a very important role as potent immune system modulation.

Licorice Root 20:1 Extract

Licorice is included for its organ and tissue protective properties. In the adrenal system and chronic stress-adaptation, licorice plays an important role in reducing the rate of loss of cortisol. Licorice slows the breakdown and thus loss of cortisol by inhibiting the enzyme 11-ß-hydroxysteroid dehydrogenase. During the chronic fatigue and long standing stress state, licorice is an important consideration for adrenal healing due to reducing daily workload as it slows down the loss of cortisol and thus decreases daily workload. This adrenal and cortisol sparing effect makes licorice that contains glycyrrhizic acid an important consideration for chronic conditions characterized by lower cortisol states and adrenal gland underfunction. In herbalism, licorice preparations are frequently used to protect the mucus membranes of the mouth and intestines, especially in conditions characterized by inflammation and ulceration like stomach ulcers associated with H pylori infections. Licorice is also used in chronic viral infections of esp liver but also the lungs, due to its ability control inflammation as well as interfere with viral replication cycles, while protecting organs from damage - can protect the mitochondria against lipid peroxidation. Licorice formulations are well recognized as being able to increase blood pressure. Judicious use of licorice in natural medicine supports conditions associated with low blood pressure, improving function. This is also the single most important caution for licorice - in sensitive individuals, overuse or co-administration with diuretics may induce high blood pressure associated with low potassium levels. *

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

All-Natural

Digestion Support

High-Potency
Ingredients

Immune Support

Vegan

Non-GMO

Satisfaction
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Customer Reviews

Based on 7 reviews
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s
s.N.
Great product

This product has been part of my comprehensive healing protocol for Chronic Neurological Lyme Disease. I have been impressed with other Return Healthy products as they've provided quick results, specifically with tick-borne illnesses that kept coming back. Adaptogen Immune greatly helps my energy levels throughout the day, especially during particularly stressful times. As always, the products are shipped out very quickly (often the same day!) and I remain impressed with Return Healthy's top notch ingredients!

G
G.
Great Product

Great product

D
D.

This is a high quality product which is making a positive difference in my life! So glad I decided to try it!

M
M.S.

Every thing was perfect. From delivery to the product, I could not have been more pleased

J
J.

I have been taking this supplement to help with general immunity for common illnesses like cold and flu. I feel this product has helped build my immune system so that I don’t get these illnesses as often as I used to.

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