Return Healthy Cryptolepis Synergy supplement bottle, a whole-herb formula for microbial and immune support.

Cryptolepis Synergy | Whole-Herb Microbial & Immune Support

$57.50
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Return Healthy Cryptolepis Synergy supplement bottle, a whole-herb formula for microbial and immune support.

Cryptolepis Synergy

Whole-Herb Microbial & Immune Support

Immunity & Inflammation Immunity & Inflammation
Named for its synergistic combination of whole‑herb Cryptolepis and complementary botanicals offering broader, balanced microbial support.

How This Formula Helps You Feel

Gentle, whole‑herb support for immune resilience, circulation, and day‑to‑day internal steadiness.

  • Gentle whole‑herb support
  • Steadier daily balance
  • Immune and circulatory resilience
$57.50
Sale price  $57.50 Regular price 
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Made in USA
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60-Day Warranty
How to Take

Take 2 capsules twice per day, with or without food, or as directed by your healthcare practitioner.

Ingredients
Cryptolepis Root
Cryptolepis sanguinolenta

Cryptolepis is a West African root used in some of the most-respected herbal protocols for microbial balance and internal resilience. The 20:1 concentration delivers a deeper botanical dose than whole-herb forms can carry. We use it in practitioner-guided formulas where the goal is supporting immune function and recovery comfort during demanding wellness phases.

Alchornea Leaf
Alchornea cordifolia

Alchornea is a leaf used in traditional West African herbal medicine to support microbial balance and immune function. It pairs well with concentrated antimicrobial botanicals and helps the body respond to physical stressors without dampening immune signaling. We include it in broader protocols where the goal is system-level rebalancing rather than targeting any single pathway.

Sida Acuta Leaf
Sida acuta

Sida acuta is a traditional immune and circulatory herb with a long history of use in concentrated botanical formulas. It supports immune function, helps maintain tissue-level response during periods of microbial stress, and contributes to healthy circulation. We use it as part of practitioner-guided protocols where a systems-based approach matters more than single-action ingredients.

Bidens Herb
Bidens pilosa

Bidens is a broad-spectrum herbal ally used in concentrated formulas focused on microbial balance and a healthy inflammatory response. It supports the gut environment alongside its immune action, which makes it useful in protocols that span both systems. We include it where the body needs steady, multi-front support rather than narrow targeting.

Dan Shen Root
Salvia miltiorrhiza

Dan Shen — Chinese red sage — is one of the most-used herbs in traditional Chinese medicine for circulation and microvascular flow. It helps move nutrients into tissues and supports organ function during periods of metabolic load. We use it where circulation is part of how the formula works, not just an afterthought.

Ceanothus Root
Ceanothus americanus

Ceanothus, also called red root, is a traditional North American herb for lymphatic flow and tissue-level drainage. It supports the body’s ability to clear and circulate fluids through the lymphatic system — the often-neglected half of circulation. We use it in detox formulas where moving things out matters as much as breaking things down.

Eupatorium Herb
Eupatorium perfoliatum

Eupatorium, commonly called boneset, is a North American herb with a long traditional record of supporting the body during periods of immune activation. It pairs well with other resilience-focused botanicals and contributes to balance when the system is actively responding. We use it where steady immune support is more useful than aggressive intervention.

Chenopodium Herb
Chenopodium ambrosioides

Chenopodium, sometimes called epazote, is a traditional digestive herb used to support gut microbial balance and a healthy internal environment. It’s included alongside other concentrated botanicals where the gut–immune axis is part of the larger picture. We use it for broad system support during periods of digestive stress.

Copaiba Essential Oil
Copaifera officinalis

Copaiba is a resin from the Amazon basin, used as an essential oil to support comfort and a balanced inflammatory response. It carries beta-caryophyllene at unusually high concentrations, which is the compound most associated with its action. We use it for tissue-level comfort and overall balance in recovery-focused formulas.

Houttuynia Herb
Houttuynia cordata

Houttuynia is a long-standing herb in East Asian traditional medicine, valued for its support of microbial balance and healthy immune signaling. It pairs naturally with other concentrated botanicals in resilience-focused formulas. We use it where the goal is maintaining a stable internal environment under microbial or environmental load — broad support, not single-target action.

Facts & Directions
Cryptolepis Synergy Supplement Facts
Cryptolepis Synergy Directions
Deep Dive: The Science

Deep Dive: The Science Behind This Formula

When the body is working to find its footing during a period of microbial stress, what it often needs is not the strongest possible push but steady, broad support it can tolerate day after day. That is the thinking behind Cryptolepis Synergy. We built it around whole-herb Cryptolepis sanguinolenta, a West African root used in some of the most respected herbal traditions for microbial balance and internal resilience, and surrounded it with a family of complementary botanicals. Using the whole herb rather than a concentrated extract preserves the full spectrum of the plant's natural compounds, which is what gives this formula its gentler, more gradual character, well suited to longer, foundational routines.

Why Whole-Herb, and Who It Suits

There is a real difference between whole-herb and extract-based support, and it matters for who should reach for each. Whole-herb Cryptolepis carries the plant's compounds in their natural balance, which the body tends to tolerate more easily and which lends itself to steady, ongoing use. We reach for this form when the goal is gradual, broad-spectrum support rather than fast, targeted intensity, particularly for people whose systems are sensitive and do not do well with aggressive shifts.

The Supporting Botanical Family

Cryptolepis does not work alone here. Alchornea cordifolia, a leaf from West African herbal medicine, supports microbial balance and immune function while helping the body respond to physical stress without dampening immune signaling. Sida acuta, a traditional immune and circulatory herb, supports immune function and healthy circulation during periods of microbial stress. Bidens pilosa adds broad-spectrum support across both the gut environment and immune response, and Houttuynia cordata, long valued in East Asian medicine, rounds out the blend with its support for a stable internal environment. Each was chosen to reinforce the others, which is where the name Synergy comes from.

Immune and Circulatory Support

Microbial balance is only part of resilience. Healthy circulation helps the body deliver nutrients, clear waste, and keep immune signaling efficient, which is why several botanicals in this formula support circulation alongside their immune action. The combination supports the kind of day-to-day steadiness that matters more over weeks and months than any single dramatic shift.

Where Cryptolepis Synergy Fits

We designed Cryptolepis Synergy for routines where consistency matters more than speed. Because it pairs whole-herb Cryptolepis with a family of supportive botanicals in their natural balance, it fits well into longer, foundational protocols, including as a gradual build-up before or alongside more concentrated support. It is broad, gentle, and built to be tolerated over time, which is exactly what many sensitive systems need.

cGMP certification icon. Why cGMP Compliance Matters

Why cGMP Compliance Matters

We don’t take shortcuts when it comes to your health. Every Return Healthy formula is made in the United States in cGMP-compliant facilities with trusted manufacturing partners who follow strict standards for cleanliness, ingredient handling, batch consistency, documentation, and quality control.

cGMP stands for Current Good Manufacturing Practices — the FDA’s framework for making sure supplements are produced with consistency and accountability. It’s not easy to maintain, and that’s why it matters.

When something becomes part of your daily health routine, it should be made with care, precision, and integrity from the first ingredient to the finished bottle.

Microscope icon. Third-Party Tested for Purity & Safety

We verify our formulas through independent third-party testing so you can feel confident about what you’re putting into your body. Testing helps confirm purity, safety, and product quality, including screening for unwanted contaminants like heavy metals, harmful microbes, and other concerns that don’t belong in a daily health routine.

For us, third-party testing is about accountability. It’s one more way we make sure every product meets the standard we’d expect for ourselves and our families.

Compare Synergy vs. Concentrate

Synergy vs. Concentrate: which one is right for you?

Both options feature Cryptolepis sanguinolenta, but they’re designed for different needs. Synergy is a gentler whole-herb approach for steady, long-term support, while Concentrate is a more potent extract used for stronger, more targeted protocols under practitioner guidance.

Quick guide

If you’re newer to herbs or tend to be sensitive, many people start with Synergy.
If you’ve used Cryptolepis before and want a stronger approach, Concentrate may be a better fit.
When in doubt, consult your healthcare practitioner.

Comparison

Feature Cryptolepis Synergy Cryptolepis Concentrate
Form Whole-herb Concentrated extract
Strength Mild, more gentle Potent, stronger
Dosage format Whole-herb powder 20:1 extract
Best for Sensitive individuals, beginning treatment, and long-term maintenance Higher-support protocols under practitioner guidance
Considerations Well-suited for gradual, sustained use May feel stronger at first, so many people start lower and increase gradually

Choose Synergy if you:

  • Are new to Cryptolepis or prefer a gentler start
  • Identify as sensitive to herbs or supplements
  • Want steady, long-term foundational support

Choose Concentrate if you:

  • Need a stronger, more concentrated option
  • Are working with a practitioner on a targeted plan
  • Understand pacing and tolerance
Vegan
All-Natural
Non-GMO
Gluten-Free
High-Potency Ingredients
Dairy-Free
Soy-Free
Microbial Balance

Built for broader, whole‑herb support with a steadier, more gradual feel.

Cryptolepis Synergy combines whole-herb Cryptolepis sanguinolenta with supportive botanicals to provide balanced microbial and immune support. As a whole-herb formula it works gradually rather than aggressively — supporting microbial balance, immune steadiness, and circulation through a balanced botanical profile that maintains day-to-day stability.

Many people researching what cryptolepis is and what it's used for choose the whole-herb form for its gentler day-to-day profile. As with any botanical, individual responses vary; review the directions and talk with your practitioner about cryptolepis benefits and how it fits your routine.

01 Day-to-day differences
  • A more steady, balanced baseline
  • Gentle daily immune and microbial support
  • Better tolerance for long‑term routines
  • Subtle improvements in energy and vitality
02 Who this is for
Cryptolepis Synergy is a good fit for individuals who prefer gentle, whole‑herb support rather than concentrated extracts. It works well for sensitive systems, longer‑term routines, foundational phases, or anyone looking for balanced microbial and immune support that doesn’t overwhelm or cause abrupt changes.
03 What to expect
Cryptolepis Synergy is designed for gradual, steady support rather than rapid or strong extract‑style shifts. Many people notice subtle improvements in energy, circulation, and internal balance over time. Because whole‑herb formulas are gentler, they tend to be well‑tolerated in long‑term routines or during foundational phases of practitioner‑guided protocols.
04 How it works
Cryptolepis Synergy combines whole‑herb Cryptolepis sanguinolenta with supportive botanicals that promote microbial balance, immune steadiness, circulation, and broader system resilience. Whole‑herb formulas provide a gentler, more gradual approach compared to concentrated extracts—making this version ideal for sensitive individuals, foundational routines, or long‑term support. The balanced botanical profile helps maintain day‑to‑day stability while supporting the body’s adaptive response.
CRYPTROLEPIS SYNERGY
What it supports

System-level benefits

Microbial Balance

Gentler, broader microbial support

Whole-herb Cryptolepis preserves a full spectrum of plant compounds that influence microbial and immune pathways gradually. Better suited for sensitive systems and long-term routines than extract-based formulas.

  • Whole-herb Cryptolepis with full spectrum compounds
  • Gentler than concentrated extracts
  • Designed for foundational and long-term routines

Inside the Formula

Ten synergistic botanicals. Whole-herb. Bioavailable.

Cryptolepis Root

Cryptolepis sanguinolenta

Cryptolepis is a West African root used in some of the most-respected herbal protocols for microbial balance and internal resilience. The 20:1 concentration delivers a deeper botanical dose than whole-herb forms can carry. We use it in practitioner-guided formulas where the goal is supporting immune function and recovery comfort during demanding wellness phases.

Alchornea Leaf

Alchornea cordifolia

Alchornea is a leaf used in traditional West African herbal medicine to support microbial balance and immune function. It pairs well with concentrated antimicrobial botanicals and helps the body respond to physical stressors without dampening immune signaling. We include it in broader protocols where the goal is system-level rebalancing rather than targeting any single pathway.

Sida Acuta Leaf

Sida acuta

Sida acuta is a traditional immune and circulatory herb with a long history of use in concentrated botanical formulas. It supports immune function, helps maintain tissue-level response during periods of microbial stress, and contributes to healthy circulation. We use it as part of practitioner-guided protocols where a systems-based approach matters more than single-action ingredients.

Bidens Herb

Bidens pilosa

Bidens is a broad-spectrum herbal ally used in concentrated formulas focused on microbial balance and a healthy inflammatory response. It supports the gut environment alongside its immune action, which makes it useful in protocols that span both systems. We include it where the body needs steady, multi-front support rather than narrow targeting.

Dan Shen Root

Salvia miltiorrhiza

Dan Shen — Chinese red sage — is one of the most-used herbs in traditional Chinese medicine for circulation and microvascular flow. It helps move nutrients into tissues and supports organ function during periods of metabolic load. We use it where circulation is part of how the formula works, not just an afterthought.

Ceanothus Root

Ceanothus americanus

Ceanothus, also called red root, is a traditional North American herb for lymphatic flow and tissue-level drainage. It supports the body’s ability to clear and circulate fluids through the lymphatic system — the often-neglected half of circulation. We use it in detox formulas where moving things out matters as much as breaking things down.

Eupatorium Herb

Eupatorium perfoliatum

Eupatorium, commonly called boneset, is a North American herb with a long traditional record of supporting the body during periods of immune activation. It pairs well with other resilience-focused botanicals and contributes to balance when the system is actively responding. We use it where steady immune support is more useful than aggressive intervention.

Chenopodium Herb

Chenopodium ambrosioides

Chenopodium, sometimes called epazote, is a traditional digestive herb used to support gut microbial balance and a healthy internal environment. It’s included alongside other concentrated botanicals where the gut–immune axis is part of the larger picture. We use it for broad system support during periods of digestive stress.

Copaiba

Copaifera officinalis

Copaiba is a resin from the Amazon basin, used as an essential oil to support comfort and a balanced inflammatory response. It carries beta-caryophyllene at unusually high concentrations, which is the compound most associated with its action. We use it for tissue-level comfort and overall balance in recovery-focused formulas.

Essential Oil

Houttuynia Herb

Houttuynia cordata

Houttuynia is a long-standing herb in East Asian traditional medicine, valued for its support of microbial balance and healthy immune signaling. It pairs naturally with other concentrated botanicals in resilience-focused formulas. We use it where the goal is maintaining a stable internal environment under microbial or environmental load — broad support, not single-target action.

What to Expect

Your recovery timeline

Cryptolepis Synergy uses whole-herb botanicals for microbial balance support. It is typically used as part of a practitioner-guided protocol.

Weeks 0-2

Your body is adjusting

Shifts in digestion, energy, or bowel habits are common as the herbs engage. Good binder support during this phase helps your body process what is being mobilized.

Weeks 3-6

Building momentum

Steadier energy, more consistent digestion, and less of the up-and-down pattern. Check in with your practitioner about how you are responding and whether adjustments are needed.

Week 7+

Deeper resilience and transition

The focus shifts to consolidating progress and supporting a more resilient internal terrain. Your practitioner will guide cycling, rotation, and transition to maintenance.

Individual results vary. Always use under the guidance of a qualified health care practitioner.

Good to know

FAQs

About This Product

What role does Cryptolepis Synergy play in a wellness routine?

It provides foundational, whole‑herb support for microbial balance, immune resilience, and circulation within daily or long‑term routines.

How is Cryptolepis Synergy different from Cryptolepis Concentrate?

Cryptolepis Synergy uses whole‑herb botanicals for gentle, broad support, while Cryptolepis Concentrate is a stronger extract‑based formula for higher‑demand protocol phases.

Can I combine Cryptolepis Synergy with other supplements?

Yes. Its gentle whole‑herb profile makes it easy to pair with broader wellness routines or practitioner‑guided protocols.

What should I expect when starting Cryptolepis Synergy?

This formula is designed for steady support rather than rapid changes. Some people notice gradual improvements in overall balance and resilience over time with consistent use.

What makes Cryptolepis Synergy different from other microbial support formulas?

Unlike stronger extract‑based formulas, Cryptolepis Synergy uses whole‑herb botanicals for gentle, steady support that is ideal for sensitive individuals or long‑term routines.

General FAQs

Can I return an opened product?

Yes — we understand that sometimes you need to try a product to know if it’s right for you.

Opened products may be eligible for store credit within 60 days of purchase. If a return label is provided, the cost may be deducted from the store credit.

How long does shipping take?

Most orders arrive within 3–6 business days, though delivery times are not guaranteed.

If you need it sooner, expedited shipping options like UPS 2nd Day Air® and UPS Next Day Air® are available at checkout.

How much does shipping cost?

Standard shipping is free on orders of $75 or more, so most orders qualify automatically.

Below $75, standard shipping is a flat $8. Expedited options, including UPS 2nd Day Air® and UPS Next Day Air®, are available at checkout if you need it sooner.

What is your return policy?

We stand behind every product we make. If something doesn’t feel right, let us know — we’ll work with you to make it right.

Unopened products can be returned within 60 days of purchase if they are in their original, sealed condition. Shipping charges are not refundable, and if a return label is provided, the cost may be deducted from your refund.

When will my order ship?

We ship quickly so you can get started right away.

Orders placed before 11:00 AM MT (Monday–Friday) typically ship the same business day. Orders placed after the cutoff, on weekends, or on holidays will ship the next business day.

Where are your products manufactured?

All of our products are manufactured in the United States in cGMP-compliant facilities.

We don’t manufacture in-house. We work with established manufacturing partners whose facilities are FDA-registered and follow Current Good Manufacturing Practices, the FDA’s framework for cleanliness, ingredient handling, batch consistency, documentation, and quality control. Every batch is produced under those documented standards.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult your health care practitioner before starting any dietary supplement or herbal regimen.

Testimonials

What our community says

  • 5 stars: 20 (95%)
  • 4 stars: 1 (5%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
A
Anonymous
Lyme help

This support gives me energy with dealing with Lyme. I don’t go a day without it!

Excellent! We have subscription options to ensure they get delivered in a time frame you choose to have it available. Keep up the good work!

D
Drongus
Useful for living in mosquito ridden Florida

This will certainly come in handy for it's known medicinal properties since I spend a lot of time outside here in FL and in the woods.

A
Anonymous
Works great

Feeling overall better when using product!

S
Steve Weiss
Great Formulation

Great formulation…(!)

S
San Gong
Eficientes

Recibido en tempo y sin daños

d
daniel benz
does it works?

after taking 2 capsules, i felt a little dizzy and then the right head inflamation in my head reduced, it hurts very bad, it does not cures but it is necessary

C
Caroline Peter
Amazing

Loving it!

B
Ben M
Helps kill Bartonella and Lyme disease

I use cryptolepis in conjunction with iodine and other meds to fight Lyme disease and Bartonella. I think cryptolepis has synergy not only with the other herbs but also with iodine and other medicines. Combined they are more powerful than they are alone. I recommend this medicine. I take two capsules per day. I would start at that because more brings on diarrhea. I plan to increase my daily dose once I finish killing my diseases and can rebuild my gut.

We love to hear everyone's experience! Thank you for sharing your tips of your wellness journey to others, keep up the good work!

B
Bodeene Amyot Cairdeas
A Gem for Babesia Infection

This product has been an absolute game-changer in my journey towards healing.

Wonderful to hear this has been such a positive impact on your wellness journey!

B
Bodeene Amyot Cairdeas
Antibabesial

Cryptolepis Synergy has been a vital part of my antibabesial treatment. Great product.

Thank you for your feedback, we love to hear how our product is supporting your needs!

C
Chelsey
5 stars

Great experience!

Thank you!

A
Anonymous
Helped Babesia

This helped. I like this blend

We love to hear it! Thank you for letting us be a part of your wellness journey!

A
Anonymous
Works great

I'm taking this on the advice of my naturopath to support my health. It is working very well.

We LOVE all of our integrated doctors, they are well diverse on herbal protocols.

A
Anonymous
Powerful Immune Support

I have been using Return Healthy's Cryptolepis Synergy for a while now, and I can confidently say that it's a game-changer when it comes to immune support. As a healthcare practitioner, I incorporate the Bruhner protocol into my practice, and Cryptolepis Synergy has become an essential part of it.This supplement is not your average immune booster; it's a comprehensive formula that supports the liver, lymphatic system, and overall immune health. The combination of ingredients in these 120 capsules is truly impressive.What I love about Cryptolepis Synergy is its effectiveness. It delivers on its promises. I've seen remarkable improvements in my patients' immune systems and overall well-being since incorporating it into their treatment plans. Whether it's for Lyme disease support or natural parasite defense, this supplement is a valuable addition to any regimen.

We love to hear from our practitioners! You need to check out our Foundation Formula which it is based on Bruhner protocol as well, it is fantastic product put together!

A
Anonymous
Helpful Lyme Disease Supplement

I use at 2 caps/day. I believe it helps with Lyme symptoms

Great, Keep at it!

N
Natalie Campbell

I don't know yet. No changes yet.

It is ok, keep taking it! Herbal supplements are gentle but effective.

A
Anonymous
Cryptolepis

Worth the spend.

One of a kind!

A
Anonymous
Seems to be doing the job

Recommended by my naturopath for treatment of Lyme disease.

It is a wonderful formula! Excellent for Lyme, specially Babesia.

A
Anonymous
Helps Lyme

A good herbal antibacterial that is good for keeping Lyme disease in check while treating fungus. Also using some herbal tinctures in conjunction with.

We are very glad to hear your feedback, thank you!

A
Amazon_Consumer
Booster

I rotate through my supplements and got this immune booster for the days that I interact with many people. These ingredients are unique and not part of my other supplements. Overall a good addition.

D
Dr. Miriam Rahav
This product works: lyne/babesia/ mycoplasma

I prescribed Cryptolepis synergy to a patient with lyme/babesia/mycoplasma and as part of his regimen this product was key in supporting his immune system to clear three infectious processes. Thank you so much!

Thank you Dr. Rahav!We wish to reach more and more patients, thank you for supporting Return Healthy and for using our products.

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